Lab report on factors influencing enzyme activity

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Lab report on factors influencing enzyme activity

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Inactivated Japanese encephalitis virus vaccine: This report summarizes the epidemiology of JE, describes the two JE vaccines that are licensed in the United States, and provides recommendations for their use among travelers and laboratory workers.

JE virus JEVa mosquito-borne flavivirus, is the most common vaccine-preventable cause of encephalitis in Asia. JE occurs throughout most of Asia and parts of the western Pacific. For most travelers to Asia, the risk for JE is very low but varies on the basis of destination, duration, season, and activities.

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JE vaccine is recommended for travelers who plan to spend a month or longer in endemic areas during the JEV transmission season and for laboratory workers with a potential for exposure to infectious JEV. JE vaccine is not recommended for short-term travelers whose visit will be restricted to urban areas or times outside of a well-defined JEV transmission season.

Two JE vaccines are licensed in the United States. Supplies of this vaccine are limited because production has ceased. Introduction Japanese encephalitis virus JEVa mosquito-borne flavivirus, is the most common vaccine-preventable cause of encephalitis in Asia 1,2.

Japanese encephalitis JE occurs throughout most of Asia and parts of the western Pacific 1,3. In endemic countries, JE is primarily a disease of children. However, travel-associated JE, although rare, can occur among persons of any age 6 For most travelers to Asia, the risk for JE is very low but varies based on destination, duration, season, and activities 9, JEV is transmitted in an enzootic cycle between mosquitoes and amplifying vertebrate hosts, primarily pigs and wading birds 11, JEV transmission occurs primarily in rural agricultural areas.

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In most temperate areas of Asia, JEV transmission is seasonal, and substantial epidemics can occur. In the subtropics and tropics, transmission can occur year-round, often intensifying during the rainy season. This report provides recommendations for use of the two JE vaccines licensed in the United States for prevention of JE among travelers and laboratory workers.

Workgroup members included persons with expertise in JE, infectious diseases, travel medicine, public health, biostatistics, immunization safety, and vaccine policy. The workgroup reviewed JE epidemiology, incidence of and risk factors for travel-associated JE disease, measures available to prevent JE disease, and the efficacy, immunogenicity, safety, cost-effectiveness, and availability of JE vaccine.

Primary sources were published, peer-reviewed studies; however, unpublished data also were considered. The workgroup held regular conference calls and met three times.

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Recommendation options were developed and discussed. When definitive research evidence was lacking, the recommendations incorporated expert opinion of the workgroup members.

The workgroup presented progress reports and preliminary recommendations to ACIP during its February and October meetings. Proposed recommendations and a draft statement were presented to ACIP and approved at the June meeting. ACIP will review additional data as these are made available, particularly regarding any adverse events following receipt of JE-VC that are reported during postmarketing surveillance studies.

Lab report on factors influencing enzyme activity

Recommendations will be updated as needed. Louis encephalitis, yellow fever, and dengue viruses 15, Four genotypes of JEV have been identified JEV is an arthropod-borne virus arbovirus that is transmitted in an enzootic cycle between mosquitoes and amplifying vertebrate hosts, primarily pigs and wading birds Figure 1 12, Because of rapid population turnover with a large number of susceptible offspring and the development of high-titered JEV viremias, domestic pigs are the most important source of infection for mosquitoes that transmit JEV to humans 11,Factors include: concentration of the enzyme, temperature, pH level, concentration of the substrate, and inhibitors.

This lab shows the affects these factors have on the rate of reaction between catalase, an enzyme found in potatoes, and hydrogen peroxide, the substrate. The specific enzyme that was studied during this lab was catalase. LAB: FACTORS INFLUENCING ENZYME ACTIVITY Background Enzymes are biological catalysts capable of speeding up chemical reactions by lowering activation energy.

One benefit of enzyme catalysts is that the cell can carry out complex chemical activities at a relatively low temperature. Persons using assistive technology might not be able to fully access information in this file. For assistance, please send e-mail to: [email protected] Accommodation and the title of the report in the subject line of e-mail.

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enzyme catalysts is that the cell can carry out complex chemical activities at a relatively low temperature. Most enzymes are proteins and their 3-dimensional shape is important to their catalytic activity.

Two specific regions on the enzyme structure play an important role in catalytic activity: the active site and the allosteric site. Type or paste a DOI name into the text box.

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Your browser will take you to a Web page (URL) associated with that DOI name. Send questions or comments to doi. Please visit our sister site, Bloat in Dogs. Knowing the symptoms and causes could save your dog's life.

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